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Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma
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Thursday, 11 July 2024, 16:00 CET | 10:00 EST
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X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
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Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain
Jun 4, 2024
MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...
Apr 14, 2020
In this study, the relative synergies of in vivo BLI, Fluorescence Imaging (FLI), and micro-CT imaging was assessed in a classic orthotopic lung cancer model from onset to late stage progression. The tumor progression study was performed using a dual bioluminescent/fluorescent reporter human lung carcinoma cell line (A549-FLuc-Neo/iRFP-Puro; Imanis Life Sciences, Rochester, MN, USA) in athymic nude female mice (Envigo RMS, Inc. Indianapolis, IN, USA). Pulmonary tumor foci were initiated by i.v. tail vein injection. Imaging was performed weekly to assess limits of detection and resolution for each modality. Ex vivo imaging was also performed. Optical imaging was performed using the In-Vivo Xtreme II optical/X-ray imaging system (Bruker BioSpin, Billerica, MA, USA), and microCT imaging was completed using the SkyScan 1176 & 1272 scanners (Bruker microCT, Kontich, Belgium).
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Related technologies: X-ray and micro computed tomography
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Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
More info at:
www.bruker.com
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