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Webinar recording: Deep dive into Spatial Biology with MERSCOPE Ultra Platform
Aug 16, 2024
We invite you to learn more about MERSCOPE Ultra Platform. Webinar featuring Rob Mathis (Global Instrument Product...
Single-Cell Genomics applications ? Ideal work for the WOLF gentle cell sorter
Aug 2, 2024
The field of genomics and computational biology has progressed immensely over the last decade and new single-cell...
Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE
Jul 16, 2024
cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for...
Theranostics: From Mice to Men and Back
Jun 25, 2024
Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma
Jun 21, 2024
RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...
Hypoxia in the Tumor Immune Microenvironment (TIME)
Jun 6, 2024
Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD
X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
Jun 5, 2024
Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain
Jun 4, 2024
MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...
Mar 26, 2020
Aggressive neurosurgical resection to achieve sustained local control is essential for prolonging survival in patients with lower-grade glioma. However, progression in many of these patients is characterized by local regrowth. Most lower-grade gliomas harbor isocitrate dehydrogenase 1 (IDH1) or IDH2 mutations, which sensitize to metabolism-altering agents. To improve local control of IDH mutant gliomas while avoiding systemic toxicity associated with metabolic therapies, a precision intraoperative treatment was developer, that couples a rapid multiplexed genotyping tool with a sustained release microparticle (MP) drug delivery system containing an IDH-directed nicotinamide phosphoribosyltransferase (NAMPT) inhibitor (GMX-1778). GMX-1778 MPs showed mutant IDH genotype-specific toxicity in vitro and in vivo, inducing regression of orthotopic IDH mutant glioma murine models.
Related technologies: Fluorescence, luminescence, X-ray, radiographic imaging
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Spectral Instruments Imaging manufactures instruments for preclinical optical (bioluminescent, fluorescent) and X-ray imaging.
More info at:
https://spectralinvivo.com/
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